The association of child maltreatment and systemic inflammation in adulthood: A systematic review.

ABSTRACT:

Introduction

Child maltreatment (CM) is associated with mental and physical health disorders in adulthood. Some studies have identified elevated markers of systemic inflammation in adult survivors of CM, and inflammation may mediate the association between CM and later health problems. However, there are methodological inconsistencies in studies of the association between CM and systemic inflammation and findings are conflicting. We performed a systematic review to examine the association of CM with systemic inflammation in adults.

Methods

A pre-registered systematic review was performed following PRISMA guidelines. Medline, Embase, Scopus and PsychInfo were searched for studies of the association of CM with blood markers of inflammation in adults. Quality was assessed using

SUBMITTER: Kerr DM 

PROVIDER: S-EPMC8031439 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature