Association of PPAR-γ2 and β3-AR Polymorphisms With Postmenopausal Hypertension.

ABSTRACT: The aim of this study was to test the association of peroxisome proliferator-activated receptor (PPAR-γ2) (Pro12Ala, C1431T) and β3-AR (Trp64Arg) polymorphisms with metabolic, nutritional, and blood pressure parameters in 271 postmenopausal women (151 hypertensive and 120 normotensive controls). The TaqMan genotyping assay and restriction fragment length polymorphism methods were used to determine the distributions of selected alleles and genotype frequencies. Nutritional status was determined by a bioimpedance method and dietary habits were assessed via 7-day dietary recall. The distribution of selected genotypes and allele frequencies did not differ between hypertensive women and normal controls after analysis by chi-square test. The postmenopausal hypertensive women were older and had h

SUBMITTER: Grygiel-Gorniak B 

PROVIDER: S-EPMC8032114 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature