Management of COVID-19-associated multisystem inflammatory syndrome in children: A comprehensive literature review.

ABSTRACT:

Background

The prevalence and severity of COVID-19 are greatly reduced in children, yet some pediatric patients develop a syndrome resembling Kawasaki Disease (KD), termed Multisystem Inflammatory Syndrome in Children (MIS-C). With an estimated incidence of 2/100,000 children, MIS-C is relatively rare but can be fatal. Clinical features can include fever, hyperinflammatory state, gastrointestinal symptoms, myocardial dysfunction, and shock. The pathogenesis of MIS-C, although yet to be completely elucidated, appears to be distinct from KD in terms of epidemiology, severity, and biochemical signature.

Aim of review

Although efficacy of treatments for MIS-C have largely not yet been investigated, we aim to conduct a comprehensive literature search of numerous medical databases

SUBMITTER: Kiss A 

PROVIDER: S-EPMC8032479 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature