A Time Duration Discrimination Task for the Study of Elapsed Time Processing in Rats.

ABSTRACT: Space and time are both essential features of episodic memory. However, while spatial tasks have been used effectively to study the behavioral relevance of place cells, the behavioral paradigms utilized for the study of time cells have not used time duration as a variable that animals need to be aware of to solve the task. In order to evaluate how time flow is coded into memory, time duration needs to be a variable that animals use to solve the behavioral task. This protocol describes a novel behavioral paradigm, the time duration discrimination (TDD) task, which is designed to directly investigate the neurological mechanisms that underlie temporal processing. During the TDD task, rats navigate around a Figure-8 Maze, which contains a rectangular track with a central arm and a delay box at

SUBMITTER: Tenney S 

PROVIDER: S-EPMC8032559 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature