Dermatomyositis and malignancy: should all patients with dermatomyositis undergo malignancy screening?

ABSTRACT: Dermatomyositis is an autoimmune disease that occurs in association with underlying malignancy in a subset of patients. Given this association, diagnosis of dermatomyositis typically triggers malignancy screening. Although various malignancy screening protocols have been proposed, none have been extensively studied or taken into account prevalence of dermatomyositis-associated malignancies. We utilized peer-reviewed manuscripts identified by a Medline search from May 2000 to April 2020 to present a focused review concerning the association between dermatomyositis and malignancy, and controversies related to screening for malignancies most commonly occurring in dermatomyositis patients. This information was then synthesized to propose a rational strategy for approaching malignancy screening

SUBMITTER: Khanna U 

PROVIDER: S-EPMC8033297 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature