Differences in the clinicopathological characteristics of pure and mixed invasive micropapillary breast carcinomas from eastern China.

ABSTRACT:

Background

Invasive micropapillary carcinoma of the breast (IMPC) is a rare pathologic subtype of breast cancer. Since the differences in the pathological features of pure and mixed IMPCs are not fully understood, we aimed to investigate the difference in clinicopathological characteristics between localized pure and mixed IMPCs.

Methods

A total of 121 localized IMPC cases were included. The clinicopathological features and survival estimates of the pure IMPC and mixed IMPC groups were compared. Targeted sequencing was performed to investigate the genomic profile of paired primary breast cancer and metastatic tissue samples from two pure IMPCs and four mixed IMPCs.

Results

Overall, 48 cases were pure IMPC and 73 were mixed IMPC. The pure group had a significantly high

SUBMITTER: Wang R 

PROVIDER: S-EPMC8033353 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature