Lung cancers and pulmonary nodules detected by computed tomography scan: a population-level analysis of screening cohorts.

ABSTRACT:

Background

An increasing number and proportion of younger lung cancer patients have been observed worldwide, raising concerns on the optimal age to begin screening. This study aimed to investigate the association between age and findings in initial CT scans.

Methods

We searched for low-dose CT screening cohorts from electronic databases. Single-arm syntheses weighted by sample size were performed to calculate the detection rates of pulmonary nodules, lung cancers (all stages and stage I), and the proportion of stage I diseases in lung cancers. In addition, we included patients who underwent chest CT in our center as a supplementary cohort. The correlation between the detection rates and age was evaluated by the Pearson Correlation Coefficient.

Results

A total of 37 st

SUBMITTER: Li C 

PROVIDER: S-EPMC8033365 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature