Ambient air pollutants are associated with morning serum cortisol in overweight and obese Latino youth in Los Angeles.

ABSTRACT:

Background

Hypothalamic-pituitary-adrenal (HPA)-axis dysfunction has been associated with a variety of mental health and cardio-metabolic disorders. While causal models of HPA-axis dysregulation have been largely focused on either pre-existing health conditions or psychosocial stress factors, recent evidence suggests a possible role for central nervous system activation via air pollutants, such as nitrogen dioxide (NO₂), ozone (O₃) and particulate matter (PM). Therefore, in an observational study of Latino youth, we investigated if monthly ambient NO₂, O₃, and PM with aerodynamic diameter ≤ 2.5 (PM_2.5) exposure were associated with morning serum cortisol levels.

Methods

In this cross-sectional study, morning serum cortis

SUBMITTER: Toledo-Corral CM 

PROVIDER: S-EPMC8034084 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature