Interactions of anthropometric indices, rs9939609 FTO gene polymorphism and breast cancer: A case-control study.

ABSTRACT: Contradictory results were reported on the effect of fat mass- and obesity-associated (FTO) gene and anthropometric measurements on breast cancer (BC). This study aimed to assess the interactions between rs9939609 polymorphism of FTO gene, anthropometric indices and BC risk in Iranian women. This case-control study was performed on 540 women including 180 women with BC and 360 healthy women in Tehran, Iran. Physical activity and dietary intakes were assessed by validated questionnaires. Data on sociodemographic and pathologic factors of the participants as well as their blood samples were collected. The rs9939609 FTO gene polymorphism was genotyped using the tetra-primer amplification refractory mutation system-polymerase chain reaction (T-ARMS-PCR). No significant association was found be

SUBMITTER: Doaei S 

PROVIDER: S-EPMC8034447 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature