Fecal Microbiota Transplantation Is Highly Effective in Real-World Practice: Initial Results From the FMT National Registry.

ABSTRACT:

Background & aims

Fecal microbiota transplantation (FMT) is used commonly for treatment of Clostridioides difficile infections (CDIs), although prospective safety data are limited and real-world FMT practice and outcomes are not well described. The FMT National Registry was designed to assess FMT methods and both safety and effectiveness outcomes from North American FMT providers.

Methods

Patients undergoing FMT in clinical practices across North America were eligible. Participating investigators enter de-identified data into an online platform, including FMT protocol, baseline patient characteristics, CDI cure and recurrence, and short and long-term safety outcomes.

Results

Of the first 259 participants enrolled at 20 sites, 222 had completed short-term follow-up at

SUBMITTER: Kelly CR 

PROVIDER: S-EPMC8034505 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature