Timing, number, and type of sexual partners associated with risk of oropharyngeal cancer.

ABSTRACT:

Background

Case-control studies from the early 2000s demonstrated that human papillomavirus-related oropharyngeal cancer (HPV-OPC) is a distinct entity associated with number of oral sex partners. Using contemporary data, we investigated novel risk factors (sexual debut behaviors, exposure intensity, and relationship dynamics) and serological markers on odds of HPV-OPC.

Methods

HPV-OPC patients and frequency-matched controls were enrolled in a multicenter study from 2013 to 2018. Participants completed a behavioral survey. Characteristics were compared using a chi-square test for categorical variables and a t test for continuous variables. Adjusted odds ratios (aOR) were calculated using logistic regression.

Results

A total of 163 HPV-OPC patients and 345 controls wer

SUBMITTER: Drake VE 

PROVIDER: S-EPMC8035131 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature