Predictors of pulmonary function at 6 years of age in infants with bronchopulmonary dysplasia.

ABSTRACT:

Rationale

Bronchopulmonary dysplasia (BPD) is a major complication of premature birth and the most common cause of chronic lung disease in infancy. Previous studies have shown that children with a history of BPD have impaired lung function in childhood compared to their term counterparts. However, little is known about potential modifiable factors that alter lung function trajectories and subsequent respiratory morbidity in this population.

Objectives

To identify potential modifiable risk factors for the development of impaired lung function in patients with a history of prematurity and bronchopulmonary dysplasia.

Methods

Growth parameters (birth, 2 years old, 6 years old) and pulmonary function testing (6 years old) were retrospectively reviewed for subjects (n = 598

SUBMITTER: Aoyama BC 

PROVIDER: S-EPMC8035215 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature