Non-alcoholic fatty liver disease in premenopausal women with polycystic ovary syndrome: A systematic review and meta-analysis.

ABSTRACT:

Background and aim

Non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) are prevalent conditions sharing common pathogenic factors. We performed a systematic literature review and meta-analysis aiming to investigate the association between NAFLD and PCOS among premenopausal PCOS patients.

Methods

Relevant studies were systematically identified from scientific databases until 2019. We calculated pooled odds ratio (OR) using a random-effect model, and heterogeneity was addressed through I ². Subgroup analyses and meta-regression for various covariates were performed.

Results

Of the 1833 studies retrieved, 23 studies with 7148 participants qualified for quantitative synthesis. The pooled result showed that women with PCOS had a

SUBMITTER: Shengir M 

PROVIDER: S-EPMC8035436 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature