Immunotherapy in Advanced Biliary Tract Cancers.
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ABSTRACT:
SUBMITTER: Boileve A
PROVIDER: S-EPMC8036747 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Publications
Immunotherapy in Advanced Biliary Tract Cancers.
Boilève Alice A Hilmi Marc M Smolenschi Cristina C Ducreux Michel M Hollebecque Antoine A Malka David D
Cancers 20210329 7
Biliary tract cancers are rare tumors with a poor prognosis. Two-thirds of these primary liver malignancies are diagnosed at advanced stages where therapeutic options are limited. Whereas several molecular targeted therapies emerge in biliary tract cancers, immunotherapy is still investigational, the only approved immunotherapy to date being the immune checkpoint inhibitor pembrolizumab for the small fraction of patients with microsatellite-instable tumors. In microsatellite-stable, pre-treated ...[more]
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