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Antimicrobial Hexaaquacopper(II) Complexes with Novel Polyiodide Chains.


ABSTRACT: The non-toxic inorganic antimicrobial agents iodine (I2) and copper (Cu) are interesting alternatives for biocidal applications. Iodine is broad-spectrum antimicrobial agent but its use is overshadowed by compound instability, uncontrolled iodine release and short-term effectiveness. These disadvantages can be reduced by forming complex-stabilized, polymeric polyiodides. In a facile, in-vitro synthesis we prepared the copper-pentaiodide complex [Cu(H2O)6(12-crown-4)5]I6 · 2I2, investigated its structure and antimicrobial properties. The chemical structure of the compound has been verified. We used agar well and disc-diffusion method assays against nine microbial reference strains in comparison to common antibiotics. The stab

SUBMITTER: Edis Z 

PROVIDER: S-EPMC8037870 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature