Passive Immunoprophylaxis against Respiratory Syncytial Virus in Children: Where Are We Now?

ABSTRACT: Respiratory syncytial virus (RSV) represents the main cause of acute respiratory tract infections in children worldwide and is the leading cause of hospitalization in infants. RSV infection is a self-limiting condition and does not require antibiotics. However hospitalized infants with clinical bronchiolitis often receive antibiotics for fear of bacteria coinfection, especially when chest radiography is performed due to similar radiographic appearance of infiltrate and atelectasis. This may lead to unnecessary antibiotic prescription, additional cost, and increased risk of development of resistance. Despite the considerable burden of RSV bronchiolitis, to date, only symptomatic treatment is available, and there are no commercially available vaccines. The only licensed passive immunoprophyl

SUBMITTER: Rocca A 

PROVIDER: S-EPMC8038138 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature