Donor Family History of ESKD and Long-term Outcomes Among African American Living Kidney Donors: A Retrospective Cohort Study.

ABSTRACT:

Rationale & objective

Live kidney donation is associated with a small increased risk for kidney disease and hypertension in African American donors. We investigated a possible association between donor family history of end-stage kidney disease (ESKD) and their postdonation kidney function and the development of hypertension. We tested whether this association was modified by kidney donation.

Study design

Retrospective cohort.

Setting & participants

Former African American live kidney donors between 1993 and 2010. Healthy nondonors were selected from the Coronary Artery Disease in Young Adults (CARDIA) Study.

Exposure

Family history of ESKD in a first-degree relative.

Outcomes

Kidney function and blood pressure ≥ 140/90 mm Hg or use of antihypertensive m

SUBMITTER: Ortigosa-Goggins M 

PROVIDER: S-EPMC8039402 | biostudies-literature | 2021 Mar-Apr

REPOSITORIES: biostudies-literature