Orthostatic Hypertension and Hypotension and Outcomes in CKD: The CRIC (Chronic Renal Insufficiency Cohort) Study.

ABSTRACT:

Rationale & objective

There are limited data about the prevalence and prognostic significance of orthostatic hypo- and hypertension in patients with chronic kidney disease. The objective of this study is to determine the prevalence of orthostatic hypo- and hypertension in a cohort of patients with chronic kidney disease and examine their association with clinical outcomes.

Study design

Prospective cohort study: Chronic Renal Insufficiency Cohort (CRIC) Study.

Setting & population

7 clinical centers, participants with chronic kidney disease.

Exposures

Orthostatic hypotension (decline in systolic blood pressure [BP] > 20 mm Hg) and orthostatic hypertension (increase in systolic BP > 20 mm Hg) from seated to standing position.

Outcomes

Cardiovascular and ki

SUBMITTER: Rouabhi M 

PROVIDER: S-EPMC8039407 | biostudies-literature | 2021 Mar-Apr

REPOSITORIES: biostudies-literature