Molecular Identification of Invasive Non-typeable Group B Streptococcus Isolates From Denmark (2015 to 2017).

ABSTRACT: The number of invasive Streptococcus agalactiae (GBS) non-typeable (NT) isolates in Denmark received since 1999 has in general accounted for 10% of all invasive GBS isolates. We present data on 55 clinical NT isolates based on clinical manifestations, clonal relationship, antimicrobial resistance (AMR) determinants, and virulence factors. The GBS isolates included in this study were phenotypic-based NT obtained from 2015 to 2017, as well as 10 reference isolates. Whole genome sequencing (WGS) was performed on all isolates and the data were analyzed for the presence of both species specific genes, capsular genes (genotype), and other relevant genes. We furthermore compared different procedures for detection of serotype specific capsular genes. Overall we were able to genotype 54 of t

SUBMITTER: Slotved HC 

PROVIDER: S-EPMC8039440 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature