Efficacy of anastrozole in the treatment of hypogonadal, subfertile men with body mass index ≥25 kg/m².

ABSTRACT:

Background

Anastrozole is a non-steroidal fourth generation aromatase inhibitor that stops the conversion of testosterone to estradiol and has been used as empiric medical therapy for the treatment of male infertility in men with an abnormal testosterone-to-estradiol ratio <10 in order to increase endogenous testosterone levels. This study sought to evaluate the efficacy of anastrozole in the treatment of hypogonadal, subfertile men with body mass index greater than 25 mg/kg² with respect to hormonal profile, semen parameters and overall fertility status.

Methods

Retrospective chart review was performed of hypogonadal, subfertile men with body mass index ≥25 kg/m² who were treated with anastrozole (1 mg daily). Hormonal measurements and semen analysis p

SUBMITTER: Shah T 

PROVIDER: S-EPMC8039603 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature