Antiplatelet and anticoagulation strategies for left ventricular assist devices.

ABSTRACT: Left ventricular assist devices (LVAD) have revolutionized the management of advanced heart failure. However, complications rates remain high, among which hemorrhagic and thrombotic complications are the most important. Antiplatelet and anticoagulation strategies form a cornerstone of LVAD management and may directly affect LVAD complications. Concurrently, LVAD complications influence anticoagulation and anticoagulation management. A thorough understanding of device, patient, and management, including anticoagulation and antiplatelet therapies, are important in optimizing LVAD outcomes. This article provides a comprehensive state of the art review of issues related to antiplatelet and anticoagulation management in LVADs. We start with a historical overview, the epidemiology and pathophysi

SUBMITTER: Loyaga-Rendon RY 

PROVIDER: S-EPMC8039667 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature