Bicarbonate Ringer's solution for early resuscitation in hemorrhagic shock rabbits.

ABSTRACT:

Background

Fluid resuscitation is important for correcting hypovolemia. Isotonic crystalloids are the preferred solution for the initial clinical management of patients with multiple traumas. Bicarbonated Ringer's solution (BRS), offering physiological levels of bicarbonate ions and electrolyte ions, can be used for supplementing missing extracellular fluid and correcting metabolic acidosis. We here investigated the effects of BRS on the resuscitation of hemorrhagic shock models and compared the resuscitation performance of three crystalloids, including BRS, acetated Ringer's solution (ARS), and normal saline.

Methods

Thirty adult male New Zealand rabbits were randomly divided into five groups (n=6): a sham operation group (Sham group), an operation without fluid therapy gro

SUBMITTER: Wang L 

PROVIDER: S-EPMC8039674 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature