Amygdala Nuclei Volume and Shape in Military Veterans With Posttraumatic Stress Disorder.

ABSTRACT:

Background

The amygdala is a subcortical structure involved in socioemotional and associative fear learning processes relevant for understanding the mechanisms of posttraumatic stress disorder (PTSD). Research in animals indicates that the amygdala is a heterogeneous structure in which the basolateral and centromedial divisions are susceptible to stress. While the amygdala complex is implicated in the pathophysiology of PTSD, little is known about the specific contributions of the individual nuclei that constitute the amygdala complex.

Methods

Military veterans (n = 355), including military veterans with PTSD (n = 149) and trauma-exposed control subjects without PTSD (n = 206), underwent high-resolution T1-weighted anatomical scans. Automated FreeSurfer segmentation of the a

SUBMITTER: Morey RA 

PROVIDER: S-EPMC8040290 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature