Ontology highlight
ABSTRACT:
SUBMITTER: Agudelo M
PROVIDER: S-EPMC8040517 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Agudelo Marianna M Palus Martin M Keeffe Jennifer R JR Bianchini Filippo F Svoboda Pavel P Salát Jiří J Peace Avery A Gazumyan Anna A Cipolla Melissa M Kapoor Tania T Guidetti Francesca F Yao Kai-Hui KH Elsterová Jana J Teislerová Dana D Chrdle Aleš A Hönig Václav V Oliveira Thiago T West Anthony P AP Lee Yu E YE Rice Charles M CM MacDonald Margaret R MR Bjorkman Pamela J PJ Růžek Daniel D Robbiani Davide F DF Nussenzweig Michel C MC
The Journal of experimental medicine 20210501 5
Tick-borne encephalitis virus (TBEV) is an emerging human pathogen that causes potentially fatal disease with no specific treatment. Mouse monoclonal antibodies are protective against TBEV, but little is known about the human antibody response to infection. Here, we report on the human neutralizing antibody response to TBEV in a cohort of infected and vaccinated individuals. Expanded clones of memory B cells expressed closely related anti-envelope domain III (EDIII) antibodies in both groups of ...[more]