Discordance of High-Sensitivity Troponin Assays in Patients With Suspected Acute Coronary Syndromes.

ABSTRACT:

Background

High-sensitivity cardiac troponin (hs-cTn) assays have different analytic characteristics.

Objectives

The goal of this study was to quantify differences between assays for common analytical benchmarks and to determine whether they may result in differences in the management of patients with suspected acute coronary syndrome (ACS).

Methods

The authors included patients with suspected ACS enrolled in the ROMICAT (Rule Out Myocardial Infarction/Ischemia Using Computer Assisted Tomography) I and II trials, with blood samples taken at emergency department presentation (ROMICAT-I and -II) or at 2 and 4 h thereafter (ROMICAT-II). hs-cTn concentrations were measured using 3 assays (Roche Diagnostics, Elecsys 2010 platform; Abbott Diagnostics, ARCHITECT i2000SR; Sie

SUBMITTER: Karady J 

PROVIDER: S-EPMC8040768 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature