A prospective study of treatments for cervical intraepithelial neoplasia and fecundability.

ABSTRACT:

Background

Treatments for cervical intraepithelial neoplasia remove precancerous cells from the cervix by excising or ablating the transformation zone. Most studies show no association between cervical intraepithelial neoplasia treatments and fertility outcomes. However, only 2 studies have examined time to pregnancy, both using retrospective study designs, with 1 study showing no association and the other showing a 2-fold increased risk of infertility (time to pregnancy >12 months) following excisional or ablative treatment.

Objective

We examined the association between cervical intraepithelial neoplasia treatments and fecundability.

Materials and methods

We analyzed data from Pregnancy Study Online (PRESTO), a prospective cohort study of North American pregnancy pla

SUBMITTER: Wise LA 

PROVIDER: S-EPMC8041134 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature