Extracorporeal multiorgan support including CO₂-removal with the ADVanced Organ Support (ADVOS) system for COVID-19: A case report.

ABSTRACT: A substantial part of COVID-19-patients suffers from multi-organ failure (MOF). We report on an 80-year old patient with pulmonary, renal, circulatory, and hepatic failure. We decided against the use of extracorporeal membrane oxygenation (ECMO) due to old age and a SOFA-score of 13. However, the patient was continuously treated with the extracorporeal multi-organ- "ADVanced Organ Support" (ADVOS) device (ADVITOS GmbH, Munich, Germany). During eight 24h-treatment-sessions blood flow (100-300 mL/min), dialysate flow (160-320 mL/min) and dialysate pH (7.6-9.0) were adapted to optimize arterial PaCO₂ and pH. Effective CO₂ removal and correction of acidosis could be demonstrated by mean arterial- versus post-dialyzer values of pCO₂ (68.7 ± 13.8 vs. 26.9 ± 11.6 

SUBMITTER: Huber W 

PROVIDER: S-EPMC8041450 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature