Impact of follow up blood cultures on outcomes of patients with community-onset gram-negative bloodstream infection.

ABSTRACT:

Background

The role of follow up blood cultures (FUBC) in the management of gram-negative bloodstream infection (GN-BSI) remains controversial. This retrospective cohort study examines the association between obtaining FUBC and mortality in GN-BSI.

Methods

Hospitalized adults with community-onset GN-BSI at Prisma Health-Midlands hospitals in South Carolina, USA from January 1, 2010 to June 30, 2015 were identified. Patients who died or were discharged from hospital within 72 h were excluded to minimize impact of survival and selection biases on results, respectively. Multivariate Cox proportional hazards regression was used to examine association between obtaining FUBC and 28-day all-cause mortality after adjustment for the propensity to obtain FUBC.

Findings

Among 76

SUBMITTER: Amipara R 

PROVIDER: S-EPMC8042341 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature