Dataset Information

Using Z-score to optimize population-specific DDH screening: a retrospective study in Hangzhou, China.

ABSTRACT:

Background

DDH (Developmental Dysplasia of the Hip) screening can potentially avert many morbidities and reduce costs. The debate about universal vs. selective DDH ultrasonography screening in different countries revolves to a large extent around effectiveness, cost, and the possibility of overdiagnosis and overtreatment. In this study, we proposed and evaluated a Z-score enhanced Graf method to optimize population-specific DDH screening.

Methods

A total of 39,710 history ultrasonography hip examinations were collected to establish a sex, side specific and age-based Z-scores model using the local regression method. The correlation between Z-scores and classic Graf types was analyzed. Four thousand two hundred twenty-nine cases with follow-up ultrasonographic examinations and 5284 cases with follow-up X-ray examinations were used to evaluate the false positive rate of the first examination based on the subsequent examinations. The results using classic Graf types and the Z-score enhanced types were compared.

Results

The Z-score enhanced Graf types were highly correlated with the classic Graf's classification (R = 0.67, p < 0.001). Using the Z-scores ≥2 as a threshold could reduce by 86.56 and 80.44% the false positives in the left and right hips based on the follow-up ultrasonographic examinations, and reduce by 78.99% false-positive cases based on the follow-up X-ray examinations, respectively.

Conclusions

Using an age, sex and side specific Z-scores enhanced Graf's method can better control the false positive rate in DDH screening among different populations.

SUBMITTER: Li H

PROVIDER: S-EPMC8042719 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Publications

Using Z-score to optimize population-specific DDH screening: a retrospective study in Hangzhou, China.

Li Haomin H Shu Liqi L Yu Jin J Xian Zeng Z Duan Huilong H Shu Qiang Q Ye Jingjing J

BMC musculoskeletal disorders 20210412 1

<h4>Background</h4>DDH (Developmental Dysplasia of the Hip) screening can potentially avert many morbidities and reduce costs. The debate about universal vs. selective DDH ultrasonography screening in different countries revolves to a large extent around effectiveness, cost, and the possibility of overdiagnosis and overtreatment. In this study, we proposed and evaluated a Z-score enhanced Graf method to optimize population-specific DDH screening.<h4>Methods</h4>A total of 39,710 history ultrason ...[more]

PMID: 33845817

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Dataset Information

Using Z-score to optimize population-specific DDH screening: a retrospective study in Hangzhou, China.

Background

Methods

Results

Conclusions

Publications

Using Z-score to optimize population-specific DDH screening: a retrospective study in Hangzhou, China.

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