Degree of Functional Divergence in Duplicates Is Associated with Distinct Roles in Plant Evolution.

ABSTRACT: Gene duplication is a major mechanism to create new genes. After gene duplication, some duplicated genes undergo functionalization, whereas others largely maintain redundant functions. Duplicated genes comprise various degrees of functional diversification in plants. However, the evolutionary fate of high and low diversified duplicates is unclear at genomic scale. To infer high and low diversified duplicates in Arabidopsis thaliana genome, we generated a prediction method for predicting whether a pair of duplicate genes was subjected to high or low diversification based on the phenotypes of knock-out mutants. Among 4,017 pairs of recently duplicated A. thaliana genes, 1,052 and 600 are high and low diversified duplicate pairs, respectively. The predictions were validated based on the pheno

SUBMITTER: Ezoe A 

PROVIDER: S-EPMC8042753 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature