Ambient air pollution exposure and radiographic pulmonary vascular volumes.

ABSTRACT: Exposure to higher levels of ambient air pollution is a known risk factor for cardiovascular disease but long-term effects of pollution exposure on the pulmonary vessels are unknown.

Methods

Among 2428 Framingham Heart Study participants who underwent chest computed tomography (CT) between 2008 and 2011, pulmonary vascular volumes were calculated by image analysis, including the total vascular volume and small vessel volume (cross-sectional area <5 mm²; BV5 defined as small vessel volume). Using spatiotemporal models and participant home address, we assigned 1-year (2008) and 5-year (2004-2008) average concentrations of fine particulate matter (PM_2.5), elemental carbon (EC), and ground-level ozone (O₃), and distance to major roadway. We examined asso

SUBMITTER: Synn AJ 

PROVIDER: S-EPMC8043731 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature