COVID-19 as a worldwide selective event and bitter taste receptor polymorphisms: An ecological correlational study.

ABSTRACT:

Background

Given the observed olfactory and gustatory dysfunctions in patients with COVID-19 and recent findings on taste receptors possible important activities in the immune system, we elected to estimate the correlation between COVID-19 mortality and polymorphism of a particular type of bitter taste receptor gene called TAS2R38, in a worldwide epidemiological point of view.

Methods

Pooled rate of each of the rs713598, rs1726866, rs10246939, and PAV/AVI polymorphisms of the TAS2R38 gene was obtained in different countries using a systematic review methodology and its relationship with the mortality of COVID-19. Data were analyzed by the comprehensive meta-analysis software and SPSS.

Results

There was only a significant reverse Pearson correlation in death counts and

SUBMITTER: Parsa S 

PROVIDER: S-EPMC8043766 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature