Preconception Thyrotropin Levels and Risk of Adverse Pregnancy Outcomes in Chinese Women Aged 20 to 49 Years.

ABSTRACT:

Importance

Maternal thyrotropin levels during gestation have a profound effect on pregnancy outcomes; however, few studies to date have evaluated the importance of preconception thyrotropin levels.

Objective

To investigate the associations between preconception thyrotropin levels and pregnancy outcomes.

Design, setting, and participants

This population-based cohort study enrolled Chinese women aged 20 to 49 years from the National Free Prepregnancy Checkups Project in China. Participants conceived within 6 months after the thyrotropin examination and completed follow-up for pregnancy outcomes between January 1, 2013, and December 31, 2017. Data were analyzed between May 1, 2019, and March 31, 2020.

Exposures

Levels of thyrotropin within 6 months before pregnanc

SUBMITTER: Yang Y 

PROVIDER: S-EPMC8044736 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature