Production of Biopolyamide Precursors 5-Amino Valeric Acid and Putrescine From Rice Straw Hydrolysate by Engineered <i>Corynebacterium glutamicum</i>.

ABSTRACT: The non-proteinogenic amino acid 5-amino valeric acid (5-AVA) and the diamine putrescine are potential building blocks in the bio-polyamide industry. The production of 5-AVA and putrescine using engineered Corynebacterium glutamicum by the co-consumption of biomass-derived sugars is an attractive strategy and an alternative to their petrochemical synthesis. In our previous work, 5-AVA production from pure xylose by C. glutamicum was shown by heterologously expressing xylA from Xanthomonas campestris and xylB from C. glutamicum. Apart from this AVA Xyl culture, the heterologous expression of xylA _Xc and xylB _Cg was also carried out in a putrescine producing C. glutamicum to engineer a PUT Xyl

SUBMITTER: Sasikumar K 

PROVIDER: S-EPMC8044859 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature