Continued versus discontinued oxytocin stimulation in the active phase of labour (CONDISOX): double blind randomised controlled trial.

ABSTRACT:

Objective

To determine whether discontinuing oxytocin stimulation in the active phase of induced labour is associated with lower caesarean section rates.

Design

International multicentre, double blind, randomised controlled trial.

Setting

Nine hospitals in Denmark and one in the Netherlands between 8 April 2016 and 30 June 2020.

Participants

1200 women stimulated with intravenous oxytocin infusion during the latent phase of induced labour.

Intervention

Women were randomly assigned to have their oxytocin stimulation discontinued or continued in the active phase of labour.

Main outcome measure

Delivery by caesarean section.

Results

A total of 607 women were assigned to discontinuation and 593 to continuation of the oxytocin infusion. The rate

SUBMITTER: Boie S 

PROVIDER: S-EPMC8044921 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature