Analysis of temporal gene regulation of Listeria monocytogenes revealed distinct regulatory response modes after exposure to high pressure processing.

ABSTRACT:

Background

The pathogen Listeria (L.) monocytogenes is known to survive heat, cold, high pressure, and other extreme conditions. Although the response of this pathogen to pH, osmotic, temperature, and oxidative stress has been studied extensively, its reaction to the stress produced by high pressure processing HPP (which is a preservation method in the food industry), and the activated gene regulatory network (GRN) in response to this stress is still largely unknown.

Results

We used RNA sequencing transcriptome data of L. monocytogenes (ScottA) treated at 400 MPa and 8^∘C, for 8 min and combined it with current information in the literature to create a transcriptional regulation database, depicting the relationship between transcription factors (TFs) and their targ

SUBMITTER: Nikparvar B 

PROVIDER: S-EPMC8045354 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature