Synthesis and self-assembly of curcumin-modified amphiphilic polymeric micelles with antibacterial activity.

ABSTRACT:

Background

The ubiquitous nature of bacterial biofilms combined with the enhanced resistance towards antimicrobials has led to the development of an increasing number of strategies for biofilm eradication. Such strategies must take into account the existence of extracellular polymeric substances, which obstruct the diffusion of antibiofilm agents and assists in the maintenance of a well-defended microbial community. Within this context, nanoparticles have been studied for their drug delivery efficacy and easily customised surface. Nevertheless, there usually is a requirement for nanocarriers to be used in association with an antimicrobial agent; the intrinsically antimicrobial nanoparticles are most often made of metals or metal oxides, which is not ideal from ecological and biomed

SUBMITTER: Barros CHN 

PROVIDER: S-EPMC8045376 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature