Atypical spatiotemporal activation of cerebellar lobules during emotional face processing in adolescents with autism.

ABSTRACT: Autism spectrum disorder (ASD) is characterized by social deficits and atypical facial processing of emotional expressions. The underlying neuropathology of these abnormalities is still unclear. Recent studies implicate cerebellum in emotional processing; other studies show cerebellar abnormalities in ASD. Here, we elucidate the spatiotemporal activation of cerebellar lobules in ASD during emotional processing of happy and angry faces in adolescents with ASD and typically developing (TD) controls. Using magnetoencephalography, we calculated dynamic statistical parametric maps across a period of 500 ms after emotional stimuli onset and determined differences between group activity to happy and angry emotions. Following happy face presentation, adolescents with ASD exhibited only left-hemisp

SUBMITTER: Styliadis C 

PROVIDER: S-EPMC8046060 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature