Breakpoints for the Classification of Anti-Candida Compounds in Antifungal Screening.

ABSTRACT:

Introduction

The absence of a standardized classification scheme for the antifungal potency of compounds screened against Candida species may hinder the study of new drugs. This systematic review proposes a scheme of interpretative breakpoints for the minimum inhibitory concentration (MIC) of bioactive compounds against Candida species in in vitro tests.

Materials and methods

A literature search was conducted in the PubMed, Scopus, Web of Science, Lilacs, and SciFinder databases for the period from January 2015 to April 2020. The following inclusion criterion was used: organic compounds tested by the microdilution technique according to the Clinical and Laboratory Standards Institute protocol against reference strains of the genus Candida. A total

SUBMITTER: Alves DDN 

PROVIDER: S-EPMC8046529 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature