Validation of a biomarker tool capable of measuring the absorbed dose soon after exposure to ionizing radiation.

ABSTRACT: A radiological or nuclear attack could involve such a large number of subjects as to overwhelm the emergency facilities in charge. Resources should therefore be focused on those subjects needing immediate medical attention and care. In such a scenario, for the triage management by first responders, it is necessary to count on efficient biological dosimetry tools capable of early detection of the absorbed dose. At present the validated assays for measuring the absorbed dose are dicentric chromosomes and micronuclei counts, which require more than 2-3 days to obtain results. To overcome this limitation the NATO SPS Programme funded an Italian-Egyptian collaborative project aimed at validating a fast, accurate and feasible tool for assessing the absorbed dose early after radiation exposure. B

SUBMITTER: Giovanetti A 

PROVIDER: S-EPMC8047015 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature