The effectiveness and safety of LMWH for preventing thrombosis in patients with spinal cord injury: a meta-analysis.

ABSTRACT:

Background

Unfractionated heparin (UFH) and low molecular weight heparin (LMWH) are commonly used for preventing venous thrombosis of the lower extremity in patients with traumatic spinal cord injury. Although, LMWH is the most commonly used drug, it has yet to be established whether it is more effective and safer than UFH. Further, a comparison of the effectiveness of LMWH in preventing thrombosis at different locations and different degrees of spinal cord injury has also not been clearly defined.

Materials and methods

Cohort studies comparing the use of LMWH and UFH in the prevention of lower limb venous thrombosis in patients with spinal cord injury were identified using PubMed. The risk of bias and clinical relevance of the included studies were assessed using forest plo

SUBMITTER: Lin Z 

PROVIDER: S-EPMC8048068 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature