Adjuvant pharmacological and surgical therapy for testicular torsion: Current state of the art.

ABSTRACT:

Introduction

Although the consequences of testicular torsion (TT) have been recognized for centuries, little progress has been made to improve outcomes beyond those seen with timely scrotal exploration. Even with testicular salvage, ischemia/reperfusion injury cause significant atrophy and functional impairment. Recent efforts have sought to identify adjuvant pharmacological or surgical interventions that may attenuate these consequences. In this review, we assess the evidence supporting clinical use of these nascent interventions.

Methods

We conducted a review of the literature published from 2000 to 2020, using the search terms "torsion", "testicular", "reperfusion", "ischemia", and "injury". Clinical and laboratory research focused on adjuvant pharmacological and surgical

SUBMITTER: Thaker H 

PROVIDER: S-EPMC8048197 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature