Evidence of a disability paradox in patient-reported outcomes in haemophilia.

ABSTRACT:

Introduction

People with inherited and long-term conditions such as haemophilia have been shown to adapt to their levels of disability, often reporting better quality of life (QoL) than expected from the general population (the disability paradox).

Aim

To investigate the disability paradox in people with haemophilia in the United States by examining preference differences in health state valuations versus the general population.

Methods

We conducted a discrete choice experiment including duration to capture valuations of health states based on patient-reported preferences. Participants indicated their preferences for hypothetical health states using the EQ-5D-5L, where each participant completed 15 of the 120 choice tasks. Response inconsistencies were evaluated with

SUBMITTER: O'Hara J 

PROVIDER: S-EPMC8048516 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature