The influence of clinical severity and topical antimicrobial treatment on bacteriological culture and the microbiota of equine pastern dermatitis.

ABSTRACT:

Background

Equine pastern dermatitis (EPD) is a common dermatological problem in horses, yet its aetiology and pathogenesis are poorly understood.

Objectives

This study aimed to investigate the effects of lesion severity and topical antimicrobial treatment on bacterial flora of EPD-affected skin.

Animals

Sixteen horses with EPD were investigated.

Methods and materials

An observational study was conducted by assigning a clinical severity score ranging from 0 (macroscopically nonlesional) to 21 (severe), and sampling the most and least severely affected limbs of 16 horses (32 limbs) for bacteriological culture and 16S rRNA sequencing. Topical antimicrobial treatment in the month before sampling was recorded. The limbs were allocated to a nonlesional or mildly aff

SUBMITTER: Sangiorgio DB 

PROVIDER: S-EPMC8048527 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature