Beyond the Health Deficit Count: Examining Deficit Patterns in a Deficit-Accumulation Frailty Index.

ABSTRACT:

Background/objectives

Exploring deficit patterns among frail people may reveal subgroups of different prognostic importance.

Design

Analysis of National Health and Aging Trends Study.

Setting

Community.

Participants

Community dwelling older adults with mild to moderate frailty (deficit-accumulation frailty index (FI) of 0.25-0.40) (n = 1821).

Measurements

Latent class analysis identified distinct clinical subgroups based on comorbidity (range: 0-10), National Health and Aging Trends Study dementia classification, and short physical performance battery (SPPB) (range: 0-12). Survival analyses compared 5-year mortality by subgroups.

Results

Three latent classes existed: Class 1 (n = 831, mean FI = 0.30) had 2.7% probable dementia, high comorbidities

SUBMITTER: Olivieri-Mui BL 

PROVIDER: S-EPMC8049510 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature