SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study.

ABSTRACT:

Background

Whether young adults who are infected with SARS-CoV-2 are at risk of subsequent infection is uncertain. We investigated the risk of subsequent SARS-CoV-2 infection among young adults seropositive for a previous infection.

Methods

This analysis was performed as part of the prospective COVID-19 Health Action Response for Marines study (CHARM). CHARM included predominantly male US Marine recruits, aged 18-20 years, following a 2-week unsupervised quarantine at home. After the home quarantine period, upon arrival at a Marine-supervised 2-week quarantine facility (college campus or hotel), participants were enrolled and were assessed for baseline SARS-CoV-2 IgG seropositivity, defined as a dilution of 1:150 or more on receptor-binding domain and full-length spike prote

SUBMITTER: Letizia AG 

PROVIDER: S-EPMC8049591 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature