Relationship Between Gestational Age and Outcomes After Congenital Heart Surgery.

ABSTRACT:

Background

Previous studies suggest that birth before 39 weeks' gestational age (GA) is associated with higher perioperative mortality and morbidity after congenital heart surgery. The optimal approach to timing of cardiac operation in premature infants remains unclear. We investigated the impact of GA at birth and corrected GA at surgery on postoperative outcomes using the Pediatric Cardiac Critical Care Consortium (PC⁴) database.

Methods

Infants undergoing selected index cardiac operations before the end of the neonatal period were included (n = 2298). GA at birth and corrected GA at the time of the index cardiac operation were used as categorical predictors and fitted as a cubic spline to assess nonlinear relationships. The primary outcome was hospital mortalit

SUBMITTER: Savorgnan F 

PROVIDER: S-EPMC8052379 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature