Effect of perioperative bronchodilator therapy on postoperative pulmonary function among lung cancer patients with COPD.

ABSTRACT: Chronic obstructive pulmonary disease (COPD), an established risk factor for lung cancer, remains largely undiagnosed and untreated before lung cancer surgery. We evaluated the effect of perioperative bronchodilator therapy on lung function changes in COPD patients who underwent surgery for non-small cell lung cancer (NSCLC). From a database including NSCLC patients undergoing lung resection, COPD patients were identified and divided into two groups based on the use of bronchodilator during the pre- and post-operative period. Changes in forced expiratory volume in 1 s (FEV₁) and postoperative complications were compared between patients treated with and without bronchodilators. Among 268 COPD patients, 112 (41.8%) received perioperative bronchodilator, and 75% (84/112) were newl

SUBMITTER: Shin SH 

PROVIDER: S-EPMC8052420 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature