Candida Empyema Thoracis at Two Academic Medical Centers: New Insights Into Treatment and Outcomes.

ABSTRACT:

Background

Candida empyema thoracis (pleural empyema) is an uncommon manifestation of invasive candidiasis, for which optimal treatment is unknown.

Methods

This is a retrospective study of patients with Candida empyema at 2 academic medical centers from September 2006 through December 2015.

Results

We identified 81 patients with Candida empyema (median age, 62 years; 68% men). Sixty-five percent of patients underwent surgery or an invasive intervention of the thorax or abdomen within the preceding 90 days. Candida empyema originated from intrathoracic (51%) or intra-abdominal sources (20%), spontaneous esophageal rupture (12%), pleural space manipulation (9%), and pneumonia (6%). Eighty-four percent and 41% of patients were intensive care u

SUBMITTER: Senger SS 

PROVIDER: S-EPMC8052497 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature