Social cognition in 22q11.2 deletion syndrome and idiopathic developmental neuropsychiatric disorders.

ABSTRACT:

Background

22q11.2 deletion syndrome (22q11DS) is a common recurrent neurogenetic condition associated with elevated risk for developmental neuropsychiatric disorders and intellectual disability. Children and adults with 22q11DS often exhibit marked social impairment as well as neurocognitive deficits, and have elevated rates of both autism spectrum disorder (ASD) and psychosis. However, the relationship between the basic processes of social cognition and cognitive ability has not been well studied in 22q11DS. Here, we examined differences in social cognition in 22q11DS, relative to multiple groups of idiopathic neuropsychiatric disorders, and typically developing healthy controls (HC). Additionally, we examined differences in intellectual functioning and its relationship to social

SUBMITTER: Jalal R 

PROVIDER: S-EPMC8052741 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature